Partly Fermented Infant Formulae With Specific Oligosaccharides Support Adequate Infant Growth and Are Well-Tolerated
Identifieur interne : 000026 ( Main/Exploration ); précédent : 000025; suivant : 000027Partly Fermented Infant Formulae With Specific Oligosaccharides Support Adequate Infant Growth and Are Well-Tolerated
Auteurs : Frédéric Huet [France] ; Marieke Abrahamse-Berkeveld [Pays-Bas] ; Sebastian Tims [Pays-Bas] ; Umberto Simeoni [Suisse] ; Gérard Beley ; Christoph Savagner [France] ; Yvan Vandenplas [Belgique] ; Jonathan O Hourihane [Irlande (pays)]Source :
- Journal of Pediatric Gastroenterology and Nutrition [ 0277-2116 ] ; 2016.
Abstract
Fermented formulae (FERM) and a specific mixture of 90% short-chain galacto-oligosaccharides and 10% long-chain fructo-oligosaccharides (scGOS/lcFOS; 9:1) have a potential beneficial effect on gastrointestinal function and microbiota development in infants. The present study assessed the safety and tolerance of the combination of partly fermented infant milk formulae and scGOS/lcFOS compared with either 1 feature, in healthy term infants.
Four hundred thirty-two infants were enrolled before 28 days of age and followed up to 17 weeks of age and assigned to 1 of the 4 groups: (i) formula with scGOS/lcFOS, (ii) scGOS/lcFOS + 15% FERM, (iii) scGOS/lcFOS + 50% FERM, or (iv) 50% fermented formula (50% FERM). Primary outcome was daily weight gain during intervention (equivalence criterion: difference in daily weight gain ≤3 g/day). Infants’ anthropometrics, formula intake, number, and type of (serious) AEs were monitored monthly. Stool samples were collected at baseline and after 17 weeks for analysis of physiological and microbiological parameters.
Equivalence of weight gain per day was demonstrated in both the intention-to-treat and per-protocol population, with a mean weight gain (SD) of 29.7 (6.1), 28.2 (4.8), 28.5 (5.0), and 28.7 (5.9) g/day for the groups i to iv respectively. No differences were observed in other growth parameters, formula intake, and the number or severity of AEs. In all scGOS/lcFOS-containing formulae, a beneficial effect of scGOS/lcFOS was observed, indicated by the lower pH, lower
The partly fermented infant milk formulae containing the specific mixture scGOS/lcFOS were well-tolerated and resulted in normal growth in healthy infants.
Url:
DOI: 10.1097/MPG.0000000000001360
PubMed: 27472478
PubMed Central: 5051523
Affiliations:
- Belgique, France, Irlande (pays), Pays-Bas, Suisse
- Canton de Vaud, Région de Bruxelles-Capitale, Utrecht (province)
- Angers, Bruxelles, Dijon, Lausanne, Utrecht
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000394
- to stream Pmc, to step Curation: 000394
- to stream Pmc, to step Checkpoint: 000021
- to stream Ncbi, to step Merge: 000464
- to stream Ncbi, to step Curation: 000464
- to stream Ncbi, to step Checkpoint: 000464
- to stream Main, to step Merge: 000026
- to stream Main, to step Curation: 000026
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Partly Fermented Infant Formulae With Specific Oligosaccharides Support Adequate Infant Growth and Are Well-Tolerated</title><author><name sortKey="Huet, Frederic" sort="Huet, Frederic" uniqKey="Huet F" first="Frédéric" last="Huet">Frédéric Huet</name><affiliation wicri:level="1"><nlm:aff id="aff1">Hôpital d’Enfants, Dijon, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Hôpital d’Enfants, Dijon</wicri:regionArea><placeName><settlement type="city">Dijon</settlement></placeName></affiliation></author><author><name sortKey="Abrahamse Berkeveld, Marieke" sort="Abrahamse Berkeveld, Marieke" uniqKey="Abrahamse Berkeveld M" first="Marieke" last="Abrahamse-Berkeveld">Marieke Abrahamse-Berkeveld</name><affiliation wicri:level="3"><nlm:aff id="aff2">Nutricia Research, Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Nutricia Research, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Tims, Sebastian" sort="Tims, Sebastian" uniqKey="Tims S" first="Sebastian" last="Tims">Sebastian Tims</name><affiliation wicri:level="3"><nlm:aff id="aff2">Nutricia Research, Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Nutricia Research, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Simeoni, Umberto" sort="Simeoni, Umberto" uniqKey="Simeoni U" first="Umberto" last="Simeoni">Umberto Simeoni</name><affiliation wicri:level="3"><nlm:aff id="aff3">Center Hospitalier Universitaire Vaudois, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Center Hospitalier Universitaire Vaudois, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Beley, Gerard" sort="Beley, Gerard" uniqKey="Beley G" first="Gérard" last="Beley">Gérard Beley</name><affiliation><nlm:aff id="aff4">Maison de l’enfant Essey- lès- Nancy, Essey- lès- Nancy</nlm:aff><wicri:noCountry code="subfield">Essey- lès- Nancy</wicri:noCountry></affiliation></author><author><name sortKey="Savagner, Christoph" sort="Savagner, Christoph" uniqKey="Savagner C" first="Christoph" last="Savagner">Christoph Savagner</name><affiliation wicri:level="1"><nlm:aff id="aff5">Center Hospitalier Universitaire d’Angers, Angers, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Center Hospitalier Universitaire d’Angers, Angers</wicri:regionArea><placeName><settlement type="city">Angers</settlement></placeName></affiliation></author><author><name sortKey="Vandenplas, Yvan" sort="Vandenplas, Yvan" uniqKey="Vandenplas Y" first="Yvan" last="Vandenplas">Yvan Vandenplas</name><affiliation wicri:level="3"><nlm:aff id="aff6">Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Hourihane, Jonathan O" sort="Hourihane, Jonathan O" uniqKey="Hourihane J" first="Jonathan O" last="Hourihane">Jonathan O Hourihane</name><affiliation wicri:level="1"><nlm:aff id="aff7">Department of Paediatrics and Child Health, University College, Cork, Ireland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Irlande (pays)</country><wicri:regionArea>Department of Paediatrics and Child Health, University College, Cork</wicri:regionArea><wicri:noRegion>Cork</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27472478</idno><idno type="pmc">5051523</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051523</idno><idno type="RBID">PMC:5051523</idno><idno type="doi">10.1097/MPG.0000000000001360</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000394</idno><idno type="wicri:Area/Pmc/Curation">000394</idno><idno type="wicri:Area/Pmc/Checkpoint">000021</idno><idno type="wicri:Area/Ncbi/Merge">000464</idno><idno type="wicri:Area/Ncbi/Curation">000464</idno><idno type="wicri:Area/Ncbi/Checkpoint">000464</idno><idno type="wicri:doubleKey">0277-2116:2016:Huet F:partly:fermented:infant</idno><idno type="wicri:Area/Main/Merge">000026</idno><idno type="wicri:Area/Main/Curation">000026</idno><idno type="wicri:Area/Main/Exploration">000026</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Partly Fermented Infant Formulae With Specific Oligosaccharides Support Adequate Infant Growth and Are Well-Tolerated</title><author><name sortKey="Huet, Frederic" sort="Huet, Frederic" uniqKey="Huet F" first="Frédéric" last="Huet">Frédéric Huet</name><affiliation wicri:level="1"><nlm:aff id="aff1">Hôpital d’Enfants, Dijon, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Hôpital d’Enfants, Dijon</wicri:regionArea><placeName><settlement type="city">Dijon</settlement></placeName></affiliation></author><author><name sortKey="Abrahamse Berkeveld, Marieke" sort="Abrahamse Berkeveld, Marieke" uniqKey="Abrahamse Berkeveld M" first="Marieke" last="Abrahamse-Berkeveld">Marieke Abrahamse-Berkeveld</name><affiliation wicri:level="3"><nlm:aff id="aff2">Nutricia Research, Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Nutricia Research, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Tims, Sebastian" sort="Tims, Sebastian" uniqKey="Tims S" first="Sebastian" last="Tims">Sebastian Tims</name><affiliation wicri:level="3"><nlm:aff id="aff2">Nutricia Research, Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Nutricia Research, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Simeoni, Umberto" sort="Simeoni, Umberto" uniqKey="Simeoni U" first="Umberto" last="Simeoni">Umberto Simeoni</name><affiliation wicri:level="3"><nlm:aff id="aff3">Center Hospitalier Universitaire Vaudois, Lausanne, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Center Hospitalier Universitaire Vaudois, Lausanne</wicri:regionArea><placeName><settlement type="city">Lausanne</settlement><region nuts="3" type="region">Canton de Vaud</region></placeName></affiliation></author><author><name sortKey="Beley, Gerard" sort="Beley, Gerard" uniqKey="Beley G" first="Gérard" last="Beley">Gérard Beley</name><affiliation><nlm:aff id="aff4">Maison de l’enfant Essey- lès- Nancy, Essey- lès- Nancy</nlm:aff><wicri:noCountry code="subfield">Essey- lès- Nancy</wicri:noCountry></affiliation></author><author><name sortKey="Savagner, Christoph" sort="Savagner, Christoph" uniqKey="Savagner C" first="Christoph" last="Savagner">Christoph Savagner</name><affiliation wicri:level="1"><nlm:aff id="aff5">Center Hospitalier Universitaire d’Angers, Angers, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Center Hospitalier Universitaire d’Angers, Angers</wicri:regionArea><placeName><settlement type="city">Angers</settlement></placeName></affiliation></author><author><name sortKey="Vandenplas, Yvan" sort="Vandenplas, Yvan" uniqKey="Vandenplas Y" first="Yvan" last="Vandenplas">Yvan Vandenplas</name><affiliation wicri:level="3"><nlm:aff id="aff6">Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Hourihane, Jonathan O" sort="Hourihane, Jonathan O" uniqKey="Hourihane J" first="Jonathan O" last="Hourihane">Jonathan O Hourihane</name><affiliation wicri:level="1"><nlm:aff id="aff7">Department of Paediatrics and Child Health, University College, Cork, Ireland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Irlande (pays)</country><wicri:regionArea>Department of Paediatrics and Child Health, University College, Cork</wicri:regionArea><wicri:noRegion>Cork</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of Pediatric Gastroenterology and Nutrition</title><idno type="ISSN">0277-2116</idno><idno type="eISSN">1536-4801</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>ABSTRACT</title><sec><title>Objective:</title><p>Fermented formulae (FERM) and a specific mixture of 90% short-chain galacto-oligosaccharides and 10% long-chain fructo-oligosaccharides (scGOS/lcFOS; 9:1) have a potential beneficial effect on gastrointestinal function and microbiota development in infants. The present study assessed the safety and tolerance of the combination of partly fermented infant milk formulae and scGOS/lcFOS compared with either 1 feature, in healthy term infants.</p></sec><sec sec-type="methods"><title>Methods:</title><p>Four hundred thirty-two infants were enrolled before 28 days of age and followed up to 17 weeks of age and assigned to 1 of the 4 groups: (i) formula with scGOS/lcFOS, (ii) scGOS/lcFOS + 15% FERM, (iii) scGOS/lcFOS + 50% FERM, or (iv) 50% fermented formula (50% FERM). Primary outcome was daily weight gain during intervention (equivalence criterion: difference in daily weight gain ≤3 g/day). Infants’ anthropometrics, formula intake, number, and type of (serious) AEs were monitored monthly. Stool samples were collected at baseline and after 17 weeks for analysis of physiological and microbiological parameters.</p></sec><sec sec-type="results"><title>Results:</title><p>Equivalence of weight gain per day was demonstrated in both the intention-to-treat and per-protocol population, with a mean weight gain (SD) of 29.7 (6.1), 28.2 (4.8), 28.5 (5.0), and 28.7 (5.9) g/day for the groups i to iv respectively. No differences were observed in other growth parameters, formula intake, and the number or severity of AEs. In all scGOS/lcFOS-containing formulae, a beneficial effect of scGOS/lcFOS was observed, indicated by the lower pH, lower <italic>Clostridium difficile</italic> levels, and higher secretory immunoglobulin A levels.</p></sec><sec sec-type="conclusion"><title>Conclusions:</title><p>The partly fermented infant milk formulae containing the specific mixture scGOS/lcFOS were well-tolerated and resulted in normal growth in healthy infants.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Field, Cj" uniqKey="Field C">CJ Field</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Garcia, C" uniqKey="Garcia C">C Garcia</name></author><author><name sortKey="Duan, Rd" uniqKey="Duan R">RD Duan</name></author><author><name sortKey="Brevaut Malaty, V" uniqKey="Brevaut Malaty V">V Brévaut-Malaty</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jost, T" uniqKey="Jost T">T Jost</name></author><author><name sortKey="Lacroix, C" uniqKey="Lacroix C">C Lacroix</name></author><author><name sortKey="Braegger, C" uniqKey="Braegger C">C Braegger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thompson, Al" uniqKey="Thompson A">AL Thompson</name></author><author><name sortKey="Monteagudo Mera, A" uniqKey="Monteagudo Mera A">A Monteagudo-Mera</name></author><author><name sortKey="Cadenas, Mb" uniqKey="Cadenas M">MB Cadenas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reisinger, Kw" uniqKey="Reisinger K">KW Reisinger</name></author><author><name sortKey="De Vaan, L" uniqKey="De Vaan L">L de Vaan</name></author><author><name sortKey="Kramer, Bw" uniqKey="Kramer B">BW Kramer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van De Heijning, Bj" uniqKey="Van De Heijning B">BJ Van de Heijning</name></author><author><name sortKey="Berton, A" uniqKey="Berton A">A Berton</name></author><author><name sortKey="Bouritius, H" uniqKey="Bouritius H">H Bouritius</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Agostoni, C" uniqKey="Agostoni C">C Agostoni</name></author><author><name sortKey="Goulet, O" uniqKey="Goulet O">O Goulet</name></author><author><name sortKey="Kolacek, S" uniqKey="Kolacek S">S Kolacek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roy, P" uniqKey="Roy P">P Roy</name></author><author><name sortKey="Aubert Jacquin, C" uniqKey="Aubert Jacquin C">C Aubert-Jacquin</name></author><author><name sortKey="Avart, C" uniqKey="Avart C">C Avart</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thibault, H" uniqKey="Thibault H">H Thibault</name></author><author><name sortKey="Aubert Jacquin, C" uniqKey="Aubert Jacquin C">C Aubert-Jacquin</name></author><author><name sortKey="Goulet, O" uniqKey="Goulet O">O Goulet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mullie, C" uniqKey="Mullie C">C Mullie</name></author><author><name sortKey="Yazourh, A" uniqKey="Yazourh A">A Yazourh</name></author><author><name sortKey="Thibault, H" uniqKey="Thibault H">H Thibault</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wopereis, H" uniqKey="Wopereis H">H Wopereis</name></author><author><name sortKey="Oozeer, R" uniqKey="Oozeer R">R Oozeer</name></author><author><name sortKey="Knipping, K" uniqKey="Knipping K">K Knipping</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="B Ckhed, F" uniqKey="B Ckhed F">F Bäckhed</name></author><author><name sortKey="Roswall, J" uniqKey="Roswall J">J Roswall</name></author><author><name sortKey="Peng, Y" uniqKey="Peng Y">Y Peng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boehm, G" uniqKey="Boehm G">G Boehm</name></author><author><name sortKey="Stahl, B" uniqKey="Stahl B">B Stahl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stahl, B" uniqKey="Stahl B">B Stahl</name></author><author><name sortKey="Thurl, S" uniqKey="Thurl S">S Thurl</name></author><author><name sortKey="Zeng, J" uniqKey="Zeng J">J Zeng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boehm, G" uniqKey="Boehm G">G Boehm</name></author><author><name sortKey="Fanaro, S" uniqKey="Fanaro S">S Fanaro</name></author><author><name sortKey="Jelinek, J" uniqKey="Jelinek J">J Jelinek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Knol, J" uniqKey="Knol J">J Knol</name></author><author><name sortKey="Scholtens, P" uniqKey="Scholtens P">P Scholtens</name></author><author><name sortKey="Kafka, C" uniqKey="Kafka C">C Kafka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arslanoglu, S" uniqKey="Arslanoglu S">S Arslanoglu</name></author><author><name sortKey="Moro, Ge" uniqKey="Moro G">GE Moro</name></author><author><name sortKey="Schmitt, J" uniqKey="Schmitt J">J Schmitt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Moro, G" uniqKey="Moro G">G Moro</name></author><author><name sortKey="Arslanoglu, S" uniqKey="Arslanoglu S">S Arslanoglu</name></author><author><name sortKey="Stahl, B" uniqKey="Stahl B">B Stahl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scholtens, Pa" uniqKey="Scholtens P">PA Scholtens</name></author><author><name sortKey="Goossens, Da" uniqKey="Goossens D">DA Goossens</name></author><author><name sortKey="Staiano, A" uniqKey="Staiano A">A Staiano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Costalos, C" uniqKey="Costalos C">C Costalos</name></author><author><name sortKey="Kapiki, A" uniqKey="Kapiki A">A Kapiki</name></author><author><name sortKey="Apostolou, M" uniqKey="Apostolou M">M Apostolou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schmelzle, H" uniqKey="Schmelzle H">H Schmelzle</name></author><author><name sortKey="Wirth, S" uniqKey="Wirth S">S Wirth</name></author><author><name sortKey="Skopnik, H" uniqKey="Skopnik H">H Skopnik</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Decsi, T" uniqKey="Decsi T">T Decsi</name></author><author><name sortKey="Arat, A" uniqKey="Arat A">A Arató</name></author><author><name sortKey="Balogh, M" uniqKey="Balogh M">M Balogh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Magne, F" uniqKey="Magne F">F Magne</name></author><author><name sortKey="Hachelaf, W" uniqKey="Hachelaf W">W Hachelaf</name></author><author><name sortKey="Suau, A" uniqKey="Suau A">A Suau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boehm, G" uniqKey="Boehm G">G Boehm</name></author><author><name sortKey="Lidestri, M" uniqKey="Lidestri M">M Lidestri</name></author><author><name sortKey="Casetta, P" uniqKey="Casetta P">P Casetta</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bakker Zierikzee, Am" uniqKey="Bakker Zierikzee A">AM Bakker-Zierikzee</name></author><author><name sortKey="Alles, Ms" uniqKey="Alles M">MS Alles</name></author><author><name sortKey="Knol, J" uniqKey="Knol J">J Knol</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Koletzko, B" uniqKey="Koletzko B">B Koletzko</name></author><author><name sortKey="Shamir, R" uniqKey="Shamir R">R Shamir</name></author><author><name sortKey="Ashwell, M" uniqKey="Ashwell M">M Ashwell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hernell, O" uniqKey="Hernell O">O Hernell</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Garcette, K" uniqKey="Garcette K">K Garcette</name></author><author><name sortKey="Bellaiche, M" uniqKey="Bellaiche M">M Bellaïche</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Knol, J" uniqKey="Knol J">J Knol</name></author><author><name sortKey="Boehm, G" uniqKey="Boehm G">G Boehm</name></author><author><name sortKey="Lidestri, M" uniqKey="Lidestri M">M Lidestri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Scholtens, Pa" uniqKey="Scholtens P">PA Scholtens</name></author><author><name sortKey="Alliet, P" uniqKey="Alliet P">P Alliet</name></author><author><name sortKey="Raes, M" uniqKey="Raes M">M Raes</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Oozeer, R" uniqKey="Oozeer R">R Oozeer</name></author><author><name sortKey="Van Limpt, K" uniqKey="Van Limpt K">K van Limpt</name></author><author><name sortKey="Ludwig, T" uniqKey="Ludwig T">T Ludwig</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Azad, Mb" uniqKey="Azad M">MB Azad</name></author><author><name sortKey="Konya, T" uniqKey="Konya T">T Konya</name></author><author><name sortKey="Maughan, H" uniqKey="Maughan H">H Maughan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Savino, F" uniqKey="Savino F">F Savino</name></author><author><name sortKey="Castagno, E" uniqKey="Castagno E">E Castagno</name></author><author><name sortKey="Calabrese, R" uniqKey="Calabrese R">R Calabrese</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Campeotto, F" uniqKey="Campeotto F">F Campeotto</name></author><author><name sortKey="Suau, A" uniqKey="Suau A">A Suau</name></author><author><name sortKey="Kapel, N" uniqKey="Kapel N">N Kapel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mugambi, Mn" uniqKey="Mugambi M">MN Mugambi</name></author><author><name sortKey="Musekiwa, A" uniqKey="Musekiwa A">A Musekiwa</name></author><author><name sortKey="Lombard, M" uniqKey="Lombard M">M Lombard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chouraqui, Jp" uniqKey="Chouraqui J">JP Chouraqui</name></author><author><name sortKey="Grathwohl, D" uniqKey="Grathwohl D">D Grathwohl</name></author><author><name sortKey="Labaune, Jm" uniqKey="Labaune J">JM Labaune</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Puccio, G" uniqKey="Puccio G">G Puccio</name></author><author><name sortKey="Cajozzo, C" uniqKey="Cajozzo C">C Cajozzo</name></author><author><name sortKey="Meli, F" uniqKey="Meli F">F Meli</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Belgique</li><li>France</li><li>Irlande (pays)</li><li>Pays-Bas</li><li>Suisse</li></country><region><li>Canton de Vaud</li><li>Région de Bruxelles-Capitale</li><li>Utrecht (province)</li></region><settlement><li>Angers</li><li>Bruxelles</li><li>Dijon</li><li>Lausanne</li><li>Utrecht</li></settlement></list><tree><noCountry><name sortKey="Beley, Gerard" sort="Beley, Gerard" uniqKey="Beley G" first="Gérard" last="Beley">Gérard Beley</name></noCountry><country name="France"><noRegion><name sortKey="Huet, Frederic" sort="Huet, Frederic" uniqKey="Huet F" first="Frédéric" last="Huet">Frédéric Huet</name></noRegion><name sortKey="Savagner, Christoph" sort="Savagner, Christoph" uniqKey="Savagner C" first="Christoph" last="Savagner">Christoph Savagner</name></country><country name="Pays-Bas"><region name="Utrecht (province)"><name sortKey="Abrahamse Berkeveld, Marieke" sort="Abrahamse Berkeveld, Marieke" uniqKey="Abrahamse Berkeveld M" first="Marieke" last="Abrahamse-Berkeveld">Marieke Abrahamse-Berkeveld</name></region><name sortKey="Tims, Sebastian" sort="Tims, Sebastian" uniqKey="Tims S" first="Sebastian" last="Tims">Sebastian Tims</name></country><country name="Suisse"><region name="Canton de Vaud"><name sortKey="Simeoni, Umberto" sort="Simeoni, Umberto" uniqKey="Simeoni U" first="Umberto" last="Simeoni">Umberto Simeoni</name></region></country><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Vandenplas, Yvan" sort="Vandenplas, Yvan" uniqKey="Vandenplas Y" first="Yvan" last="Vandenplas">Yvan Vandenplas</name></region></country><country name="Irlande (pays)"><noRegion><name sortKey="Hourihane, Jonathan O" sort="Hourihane, Jonathan O" uniqKey="Hourihane J" first="Jonathan O" last="Hourihane">Jonathan O Hourihane</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Belgique/explor/OpenAccessBelV2/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000026 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000026 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Belgique
|area= OpenAccessBelV2
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:5051523
|texte= Partly Fermented Infant Formulae With Specific Oligosaccharides Support Adequate Infant Growth and Are Well-Tolerated
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:27472478" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a OpenAccessBelV2
| This area was generated with Dilib version V0.6.25. |  |